Shazia Amar

Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase.

A Villafania, Khandaker N. Anwar, Shazia Amar et al. · PubMed · 2000 · 41 citations

Immunology, Cell Death, Oocyte Maturation +18

Selective inhibition of oncogenic ras- p21 in vivo by agents that block its interaction with jun -N-kinase (JNK) and jun proteins. Implications for the design of selective chemotherapeutic agents

Shazia Amar, Albert Glozman, Denise Chung et al. · Cancer Chemotherapy and Pharmacology · 1997 · 27 citations

Jun Proteins, Jun -N-kinase, Medicine +7

Induction of oocyte maturation by jun -N-terminal kinase (JNK) on the oncogenic ras -p21 pathway is dependent on the raf -MEK-MAP kinase signal transduction pathway

Lyndon Chie, Shazia Amar, H F Kung et al. · Cancer Chemotherapy and Pharmacology · 2000 · 25 citations

Developmental Biology, Signal Transduction, Oncogenic Ras +9

Inhibition of Oncogenic and Activated Wild-Type ras-p21 Protein-Induced Oocyte Maturation by Peptides from the ras-Binding Domain of the raf-p74 Protein, Identified from Molecular Dynamics Calculations

Denise Chung, Shazia Amar, Albert Glozman et al. · Journal of Protein Chemistry · 1997 · 21 citations

Ras-binding Domain, Protein Function, Signal Transduction +10

Identification of the Site of Inhibition of Oncogenic ras–p21-Induced Signal Transduction by a Peptide from a ras Effector Domain

Lyndon Chie, James Chen, Fred K. Friedman et al. · Journal of Protein Chemistry · 1999 · 12 citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +7