Andrew S. Murkin

Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme

Rafael G. da Silva, Andrew S. Murkin, Vern L. Schramm · Proceedings of the National Academy of Sciences · 2011 · 114 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Azetidine Based Transition State Analogue Inhibitors of <i>N</i>-Ribosyl Hydrolases and Phosphorylases

Gary B. Evans, Richard H. Furneaux, Ben W. Greatrex et al. · Journal of Medicinal Chemistry · 2008 · 92 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening

Esther Bettiol, Marie I. Samanovic, Andrew S. Murkin et al. · PLoS neglected tropical diseases · 2009 · 86 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +15

Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model

María B. Cassera, Keith Z. Hazleton, Emilio Merino et al. · PLoS ONE · 2011 · 69 citations · Full text

Medicine, Infectious Diseases, Pharmacology +15

Third-Generation Immucillins: Syntheses and Bioactivities of Acyclic Immucillin Inhibitors of Human Purine Nucleoside Phosphorylase

Keith Clinch, Gary B. Evans, Richard Fröhlich et al. · Journal of Medicinal Chemistry · 2009 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15