Andrew S. Murkin

Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme

Rafael G. da Silva, Andrew S. Murkin, Vern L. Schramm · Proceedings of the National Academy of Sciences · 2011 · 113 citations · Full text

Azetidine Based Transition State Analogue Inhibitors of <i>N</i>-Ribosyl Hydrolases and Phosphorylases

Gary B. Evans, Richard H. Furneaux, Ben W. Greatrex et al. · Journal of Medicinal Chemistry · 2008 · 92 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +14

Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening

Esther Bettiol, Marie I. Samanovic, Andrew S. Murkin et al. · PLoS neglected tropical diseases · 2009 · 79 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Immunology +18

Third-Generation Immucillins: Syntheses and Bioactivities of Acyclic Immucillin Inhibitors of Human Purine Nucleoside Phosphorylase

Keith Clinch, Gary B. Evans, Richard Fröhlich et al. · Journal of Medicinal Chemistry · 2009 · 69 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Third-generation Immucillins +16

Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model

María B. Cassera, Keith Z. Hazleton, Emilio Merino et al. · PLoS ONE · 2011 · 68 citations · Full text

Antiparasitic Agent, Malaria, Molecular Biology +16