Kazuhide Nakamura

KRN951, a Highly Potent Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, Has Antitumor Activities and Affects Functional Vascular Properties

Kazuhide Nakamura, Eri Taguchi, Atsushi Yamamoto et al. · Cancer Research · 2006 · 209 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocytes/macrophages

Masato Murakami, Shinobu Iwai, Sachie Hiratsuka et al. · Blood · 2006 · 168 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors:  Synthesis, Structure−Activity Relationships, and Antitumor Activities of <i>N</i>-Phenyl-<i>N</i>‘-{4-(4-quinolyloxy)phenyl}ureas

Kazuo Kubo, Toshiyuki Shimizu, Shin-ichi Ohyama et al. · Journal of Medicinal Chemistry · 2005 · 146 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki et al. · Molecular Cancer Therapeutics · 2016 · 105 citations

Medicine, Molecular Biology, Oncology +13

LSD1 Inhibitor T-3775440 Inhibits SCLC Cell Proliferation by Disrupting LSD1 Interactions with SNAG Domain Proteins INSM1 and GFI1B

Shinji Takagi, Yoshinori Ishikawa, Akio Mizutani et al. · Cancer Research · 2017 · 88 citations

Life Sciences, Molecular Biology, Oncology +13