Masato Yabuki

Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of <i>C</i>-7-Substituted 1,3-Benzothiazole Derivatives

Masanori Okaniwa, Masaaki Hirose, Takeo Arita et al. · Journal of Medicinal Chemistry · 2013 · 111 citations · Full text

A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells

Yoshinori Ishikawa, Kanae Gamo, Masato Yabuki et al. · Molecular Cancer Therapeutics · 2016 · 103 citations

Demethylase 1A, Mixed-phenotype Acute Leukemia, Myeloid Neoplasia +17

Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds

Masanori Okaniwa, Masaaki Hirose, Takashi Imada et al. · Journal of Medicinal Chemistry · 2012 · 76 citations

p53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity

Ryuhei Okuyama, Eisaku Ogawa, Hirokazu Nagoshi et al. · Oncogene · 2007 · 72 citations

Lineage Plasticity, Developmental Biology, Cell Regulation +8

Design and Synthesis of Potent Inhibitor of Apoptosis (IAP) Proteins Antagonists Bearing an Octahydropyrrolo[1,2-<i>a</i>]pyrazine Scaffold as a Novel Proline Mimetic

Kentaro Hashimoto, Bunnai Saito, Naoki Miyamoto et al. · Journal of Medicinal Chemistry · 2013 · 32 citations · Full text

Chemoprevention Strategy, Potent Inhibitor, Novel Proline Mimetic +19