Toshiyuki Shimizu

Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA

Zhikuan Zhang, Umeharu Ohto, Takuma Shibata et al. · Immunity · 2016 · 417 citations · Full text

Toll-like Receptor 7, Toll-like Receptors, Dual Receptor +8

Structural basis for Ca2+-induced activation of human PAD4

Kyohei Arita, Hiroshi Hashimoto, Toshiyuki Shimizu et al. · Nature Structural & Molecular Biology · 2004 · 400 citations

Molecular Neuroscience, Signal Transduction, Molecular Physiology +10

Epigenetic Control of rDNA Loci in Response to Intracellular Energy Status

Akiko Murayama, Kazuji Ohmori, Akiko Fujimura et al. · Cell · 2008 · 391 citations · Full text

Chromatin, Intracellular Energy Status, Medicine +10

Toll-like receptor 8 senses degradation products of single-stranded RNA

Hiromi Tanji, Umeharu Ohto, Takuma Shibata et al. · Nature Structural & Molecular Biology · 2015 · 378 citations

Toll-like Receptors, Signal Transduction, Natural Sciences +6

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

Umeharu Ohto, Takuma Shibata, Hiromi Tanji et al. · Nature · 2015 · 351 citations

Toll-like Receptors, Molecular Immunology, Signal Transduction +9