Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

Kyohei Arita, Mariko Ariyoshi, Hidehito Tochio, +2

Nature

ChromatinSra Protein Uhrf1Chromatin RemodelingHemi-methylated DnaGenetics +11

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain

Junji Otani, Toshiyuki Nankumo, Kyohei Arita, +3

EMBO Reports

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationMolecular Biology +15

Structural basis for Ca2+-induced activation of human PAD4

Kyohei Arita, Hiroshi Hashimoto, Toshiyuki Shimizu, +3

Nature Structural & Molecular Biology

Molecular NeuroscienceSignal TransductionMolecular PhysiologyG Protein-coupled ReceptorPhysiology +8

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication

Atsuya Nishiyama, Luna Yamaguchi, Jafar Sharif, +9

Nature

ChromatinChromatin RemodelingNatural SciencesGeneticsEpigenetic Change +5

Inhibitors and Inactivators of Protein Arginine Deiminase 4:  Functional and Structural Characterization^,

Yuan Luo, Kyohei Arita, Monica Bhatia, +5

Biochemistry

Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1

Kyohei Arita, Shin Isogai, Takashi Oda, +9

Proceedings of the National Academy of Sciences

Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance

Satoshi Ishiyama, Atsuya Nishiyama, Yasushi Saeki, +19

Molecular Cell

Histone ModificationsChromatinHistone H3Chromatin StructureChromatin Remodeling +12

Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation

Laure Ferry, Alexandra Fournier, Takeshi Tsusaka, +19

Molecular Cell

ChromatinNatural SciencesGeneticsDna MethylationEpigenetic Change +12

Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation

Atsuya Nishiyama, Christopher B. Mulholland, Sebastian Bultmann, +16

Nature Communications

Crystal Structure of the Ubiquitin-associated (UBA) Domain of p62 and Its Interaction with Ubiquitin

Shin Isogai, Daichi Morimoto, Kyohei Arita, +8

Journal of Biological Chemistry

Crystal StructureMitophagyUbiquitin ShiftsMolecular BiologyCell Autophagy +15