CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation

Jiehui Deng, Eric S. Wang, Russell W. Jenkins, +43

Cancer Discovery

Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics

Andras Boeszoermenyi, Sandeep Chhabra, Abhinav Dubey, +12

Nature Methods

Biomolecular AnalysisAromatic 19F-13c TrosyMolecular BiologyBackground-free ApproachChemical Probe +5

DOTA-Amide Lanthanide Tag for Reliable Generation of Pseudocontact Shifts in Protein NMR Spectra

Bim Graham, Choy Theng Loh, James Swarbrick, +9

Bioconjugate Chemistry

Protein AssemblyBiomolecular Structure PredictionMagnetic ResonanceMolecular BiologyReliable Generation +15

Kv1.3 channel‐blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

Sandeep Chhabra, Shih Chieh Chang, Hai M. Nguyen, +19

The FASEB Journal

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

Harunur Rashid, Redwan Huq, Mark R. Tanner, +9

Scientific Reports

Development of Highly Selective Kv1.3-Blocking Peptides Based on the Sea Anemone Peptide ShK

Michael W. Pennington, Shih Yu Chang, Satendra Chauhan, +5

Marine Drugs

A Potent and Selective Peptide Blocker of the Kv1.3 Channel: Prediction from Free-Energy Simulations and Experimental Confirmation

M. Harunur Rashid, Germano Heinzelmann, Redwan Huq, +7

PLoS ONE

Free EnergyBiophysical ModelingPeptide EngineeringMolecular BiologyHyperpolarization (Biology) +16

Dicarba Analogues of α-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets

Sandeep Chhabra, Alessia Belgi, Peter H. Bartels, +8

Journal of Medicinal Chemistry

Pain DisordersPain MedicineSynaptic TransmissionMolecular PainPharmacotherapy +24

VPS29 Is Not an Active Metallo-Phosphatase but Is a Rigid Scaffold Required for Retromer Interaction with Accessory Proteins

James Swarbrick, Daniel Shaw, Sandeep Chhabra, +5

PLoS ONE

8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

Matthew L. Dennis, Michael D. Lee, Jitendra R. Harjani, +16

Chemistry - A European Journal