Donatella Tondi

Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

Daniela Cardinale, Giambattista Guaitoli, Donatella Tondi et al. · Proceedings of the National Academy of Sciences · 2011 · 103 citations · Full text

Peptide Engineering, Molecular Biology, Peptide Therapeutics +16

Structure-based discovery and in-parallel optimization of novelcompetitive inhibitors of thymidylate synthase

Donatella Tondi, Ursula Slomczynska, Maria Paola Costi et al. · Chemistry & Biology · 1999 · 102 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +11

Structure-Based Optimization of a Non-β-lactam Lead Results in Inhibitors That Do Not Up-Regulate β-Lactamase Expression in Cell Culture

Donatella Tondi, Federica Morandi, Richard Bonnet et al. · Journal of the American Chemical Society · 2005 · 63 citations · Full text

Structure-based Optimization, Cell Culture, Non-β-lactam Lead Results +23

Mono- and Disubstituted-3,8-diazabicyclo[3.2.1]octane Derivatives as Analgesics Structurally Related to Epibatidine:  Synthesis, Activity, and Modeling

Daniela Barlocco, Giorgio Cignarella, Donatella Tondi et al. · Journal of Medicinal Chemistry · 1998 · 53 citations · Full text

Nmr Spectroscopy, Pain Medicine, Organic Chemistry +18

Structure-Based Design of Inhibitors Specific for Bacterial Thymidylate Synthase^,

Thomas J. Stout, Donatella Tondi, Marcella Rinaldi et al. · Biochemistry · 1999 · 51 citations