Maria Paola Costi

Comprehensive Mechanistic Analysis of Hits from High-Throughput and Docking Screens against β-Lactamase

Kerim Babaoglu, Anton Simeonov, John J. Irwin et al. · Journal of Medicinal Chemistry · 2008 · 178 citations · Full text

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development

Antonio Cavazzuti, Giuseppe Paglietti, William N. Hunter et al. · Proceedings of the National Academy of Sciences · 2008 · 157 citations · Full text

Crystal Structure, Bioorganic Chemistry, Antiparasitic Agent +17

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

Natalia Realini, Carlos Ortíz-de-Solórzano, Chiara Pagliuca et al. · Scientific Reports · 2013 · 154 citations · Full text

2-Carboxyquinoxalines Kill <i>Mycobacterium tuberculosis</i> through Noncovalent Inhibition of DprE1

João Neres, Ruben C. Hartkoorn, Laurent R. Chiarelli et al. · ACS Chemical Biology · 2014 · 133 citations · Full text

Tuberculosis Prevention, Bacteriology, Molecular Biology +21

Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

Daniela Cardinale, Giambattista Guaitoli, Donatella Tondi et al. · Proceedings of the National Academy of Sciences · 2011 · 103 citations · Full text

Peptide Engineering, Molecular Biology, Peptide Therapeutics +16