The Novel Gene Encoding a Putative Transmembrane Protein Is Mutated in Gnathodiaphyseal Dysplasia (GDD)

Satoshi Tsutsumi, Nobuyuki Kamata, Tamara Vokes, +12

The American Journal of Human Genetics

BiologyDevelopmental BiologyNovel GeneGenetic DisorderNatural Sciences +9

Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants.

Takashi Yamaoka, Chiyoko Idehara, Masashi Yano, +8

Journal of Clinical Investigation

Activin ReceptorPancreas TransplantationTransgenic MiceInsulin SignalingCell Signaling +15

Prevention of adoptively transferred diabetes in nonobese diabetic mice with IL-10-transduced islet-specific Th1 lymphocytes. A gene therapy model for autoimmune diabetes.

Maki Moritani, Katsuhiko Yoshimoto, Setsuko Ii, +7

Journal of Clinical Investigation

ImmunologyPathologyImmunologic MechanismPancreas TransplantationImmunotherapy +17

SNPs in the KCNJ11-ABCC8 gene locus are associated with type 2 diabetes and blood pressure levels in the Japanese population

Yukiko Sakamoto, Hiroshi Inoue, Parvaneh Keshavarz, +10

Journal of Human Genetics

Genome-wide Association StudyJapanese PopulationGenetic DeterminantKcnj11-abcc8 Gene LocusGenetics +9

Absence of Germ-Line Mutations of the Multiple Endocrine Neoplasia Type 1 (MEN1) Gene in Familial Pituitary Adenoma in Contrast to MEN1 in Japanese1

Chisato Tanaka, Katsuhiko Yoshimoto, Shozo Yamada, +5

The Journal of Clinical Endocrinology & Metabolism

Endocrine OncologyGerm-line MutationsGerm-line MutationPituitary GlandSomatic Variant +11

Amidophosphoribosyltransferase Limits the Rate of Cell Growth-linked de Novo Purine Biosynthesis in the Presence of Constant Capacity of Salvage Purine Biosynthesis

Takashi Yamaoka, Hiroyuki Iwahana, Maki Moritani

Journal of Biological Chemistry

Constant CapacityMetabolic RateMolecular BiologyOxidative StressBiosynthesis +20

Analysis of Loss of Heterozygosity on Chromosome 11 and Infrequent Inactivation of the MEN1 Gene in Sporadic Pituitary Adenomas1

Chisato Tanaka, Takehiko Kimura, Peng Yang, +6

The Journal of Clinical Endocrinology & Metabolism

SpermatogenesisCytogeneticsGeneticsPathologyMolecular Genetics +16

The Rate of Cell Growth Is Regulated by Purine Biosynthesis via ATP Production and G1 to S Phase Transition

Masakazu Kondo, Takashi Yamaoka, Shinji Honda, +6

The Journal of Biochemistry

Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1.

Maki Moritani, Katsuhiko Yoshimoto, F. Susan Wong, +7

Journal of Clinical Investigation

Transgenic Paracrine Tgf-beta1T-regulatory CellImmunologyParacrine EffectPancreas Transplantation +17

Localization of a gene for familial juvenile hyperuricemic nephropathy causing underexcretion-type gout to 16p12 by genome-wide linkage analysis of a large family

Naoyuki Kamatani, Maki Moritani, Hisashi Yamanaka, +3

Arthritis & Rheumatism