Willem K. Smits

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

Linda Zuurbier, Irene Homminga, Valerie Calvert et al. · Leukemia · 2010 · 140 citations

Hematological Malignancy, Pediatric Hematology, Medicine +9

The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia

Linda Zuurbier, Emanuel F. Petricoin, Maartje Vuerhard et al. · Haematologica · 2012 · 124 citations · Full text

IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study

Yunlei Li, Jessica G. C. A. M. Buijs-Gladdines, Kirsten Canté-Barrett et al. · PLoS Medicine · 2016 · 102 citations · Full text

MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia

Kirsten Canté-Barrett, J A P Spijkers-Hagelstein, Jessica G. C. A. M. Buijs-Gladdines et al. · Leukemia · 2016 · 89 citations · Full text

Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors

Linda Zuurbier, Alejandro Gutiérrez, Charles G. Mullighan et al. · Haematologica · 2013 · 87 citations · Full text

Hematological Malignancy, Immature Cluster, Immature Cluster Cases +15