Urmi Dhagat

Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody

Sophie E. Broughton, Timothy R. Hercus, Matthew P. Hardy et al. · Cell Reports · 2014 · 57 citations · Full text

Life Sciences, Immunology, Oncology +17

Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling

Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero et al. · Structure · 2016 · 53 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors

Con Panousis, Urmi Dhagat, Kirsten M. Edwards et al. · mAbs · 2015 · 44 citations · Full text

Life Sciences, Immunology, Pharmacology +17

A dual role for the N-terminal domain of the IL-3 receptor in cell signalling

Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero et al. · Nature Communications · 2018 · 44 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins

Christopher G. Langendorf, Matthew T. O’Brien, Kevin R. W. Ngoei et al. · Journal of Biological Chemistry · 2020 · 42 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17