Evan G. Pappas

The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice

Tingting Ge, Gaurang Jhala, Stacey Fynch et al. · Frontiers in Immunology · 2020 · 44 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Lipotoxic Stress Induces Pancreatic<i>β</i>-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System

Sara A. Litwak, Jibran A. Wali, Evan G. Pappas et al. · Journal of Diabetes Research · 2015 · 43 citations · Full text

Life Sciences, Endocrinology, Pharmacology +10

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans

Mohammed Bensellam, Yan‐Chuan Shi, Jeng Yie Chan et al. · Diabetologia · 2019 · 28 citations · Full text

Life Sciences, Cell Biology, Endocrinology +16

Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice

Jibran A. Wali, Sandra Galić, Christina Y.R. Tan et al. · Cell Death and Differentiation · 2017 · 25 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a <scp>JAK1</scp>/<scp>JAK2</scp> inhibitor

Tingting Ge, Amber‐Lee Phung, Gaurang Jhala et al. · Clinical & Translational Immunology · 2022 · 22 citations · Full text

Life Sciences, Immunology, Oncology +17