Dopamine receptor D2 antagonism normalizes profibrotic macrophage-endothelial crosstalk in non-alcoholic steatohepatitis

Jie Qing, Yafeng Ren, Yuwei Zhang, +12

Journal of Hepatology

InflammationMetabolic Associated SteatohepatitisMedicineProfibrotic Macrophage-endothelial CrosstalkImmunology +8

Cyclophilin A Associates with Enterovirus-71 Virus Capsid and Plays an Essential Role in Viral Infection as an Uncoating Regulator

Jie Qing, Yaxin Wang, Yuna Sun, +9

PLoS Pathogens

Viral ReplicationEfficient ProliferationViral PathogenesisImmunologyMolecular Biology +15

Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking

Yu Wei, Jinlong Li, Jie Qing, +8

PLoS ONE

Drug TargetViral Polymerase StructureAntiviral DrugSystems PharmacologyMolecular Pharmacology +18

Stapled peptide-based membrane fusion inhibitors of hepatitis C virus

Hong‐Kui Cui, Jie Qing, Ye Guo, +5

Bioorganic & Medicinal Chemistry

Hepatitis C VirusAntiviral Drug DevelopmentAntiviral TherapyHepatitisVirology +3

A Conserved Inhibitory Mechanism of a Lycorine Derivative against Enterovirus and Hepatitis C Virus

Yu Guo, Yaxin Wang, Lin Cao, +6

Antimicrobial Agents and Chemotherapy

An adenosine nucleoside analogue NITD008 inhibits EV71 proliferation

Luqing Shang, Yaxin Wang, Jie Qing, +6

Antiviral Research

Cell BiologyEv71 ProliferationMolecular BiologyTumor Suppressor

Suramin inhibits EV71 infection

Yaxin Wang, Jie Qing, Yuna Sun, +1

Antiviral Research

Antiparasitic AgentEv71 InfectionPathogenesisImmunologyMechanism Of Action +3

Hippo/YAP Pathway Plays a Critical Role in Effect of GDNF Against Aβ-Induced Inflammation in Microglial Cells

Jie Qing, Xiaoheng Liu, Quan Wu, +6

DNA and Cell Biology

Microglia CellsImmunologyHippo/yap PathwayCell DeathSynaptic Signaling +19

Design and synthesis of imidazo[1,2-α][1,8]naphthyridine derivatives as anti-HCV agents via direct C–H arylation

Shengdian Huang, Jie Qing, Shuo Wang, +3

Organic & Biomolecular Chemistry

Organic ChemistryChemistryPharmaceutical ChemistryDirect C–h ArylationMedicinal Chemistry +14

Stapled Peptides Targeting SARS-CoV-2 Spike Protein HR1 Inhibit the Fusion of Virus to Its Cell Receptor

Mengjun Zheng, Wei Cong, Haoran Peng, +9

Journal of Medicinal Chemistry