Yu Guo

Common activation mechanism of class A GPCRs

Qingtong Zhou, Dehua Yang, Meng Wu et al. · eLife · 2019 · 666 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design

Xiaoyun Lu, Yuwan Liu, Yiqun Yang et al. · Nature Communications · 2019 · 276 citations · Full text

Engineering, Biochemistry, Biotechnology +15

The newly emerged SARS-Like coronavirus HCoV-EMC also has an “Achilles’ heel”: current effective inhibitor targeting a 3C-like protease

Zhi-Lin Ren, Liming Yan, Ning Zhang et al. · Protein & Cell · 2013 · 183 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

A structural view of the antibiotic degradation enzyme NDM-1 from a superbug

Yu Guo, Jing Wang, Niu Guojun et al. · Protein & Cell · 2011 · 176 citations · Full text

Life Sciences, Biochemistry, Microbiology +6

Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD

Yunjiao Zhou, Zezhong Liu, Shibo Li et al. · Cell Reports · 2021 · 142 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16