Yu Guo

Common activation mechanism of class A GPCRs

Qingtong Zhou, Dehua Yang, Meng Wu et al. · eLife · 2019 · 633 citations · Full text

Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design

Xiaoyun Lu, Yuwan Liu, Yiqun Yang et al. · Nature Communications · 2019 · 265 citations · Full text

The newly emerged SARS-Like coronavirus HCoV-EMC also has an “Achilles’ heel”: current effective inhibitor targeting a 3C-like protease

Zhi-Lin Ren, Liming Yan, Ning Zhang et al. · Protein & Cell · 2013 · 181 citations · Full text

Hcov-emc Main Protease, Viral Polymerase Structure, Infection Disease Program +19

A structural view of the antibiotic degradation enzyme NDM-1 from a superbug

Yu Guo, Jing Wang, Niu Guojun et al. · Protein & Cell · 2011 · 170 citations · Full text

Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD

Yunjiao Zhou, Zezhong Liu, Shibo Li et al. · Cell Reports · 2021 · 140 citations · Full text