Marc Nazaré

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

Dietrich Alexander Ruess, Guus J.J.E. Heynen, Katrin J. Ciecielski et al. · Nature Medicine · 2018 · 373 citations

Medicine, Molecular Biology, Oncology +14

Evidence for CCl/CBr⋅⋅⋅π Interactions as an Important Contribution to Protein–Ligand Binding Affinity

Hans Matter, Marc Nazaré, Stefan Güssregen et al. · Angewandte Chemie International Edition · 2009 · 270 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

A pharmacological master key mechanism that unlocks the selectivity filter gate in K ⁺ channels

Marcus Schewe, Han Sun, Ümit Mert et al. · Science · 2019 · 136 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

A Flexible, Palladium‐Catalyzed Indole and Azaindole Synthesis by Direct Annulation of Chloroanilines and Chloroaminopyridines with Ketones

Marc Nazaré, C.M. Schneider, A. Lindenschmidt et al. · Angewandte Chemie International Edition · 2004 · 135 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold:  A Study Combining Structure-Activity Relationship and X-ray Crystallography

Marc Nazaré, David W. Will, Hans Matter et al. · Journal of Medicinal Chemistry · 2005 · 119 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12