Pierre C. Wyss

Novel Dihydrofolate Reductase Inhibitors. Structure-Based versus Diversity-Based Library Design and High-Throughput Synthesis and Screening

Pierre C. Wyss, Paul R. Gerber, Peter Hartman et al. · Journal of Medicinal Chemistry · 2003 · 70 citations · Full text

Combinatorial Chemistry, Antibacterial Activity, Organic Chemistry +19

The synthesis of <scp>DL</scp>‐1‐(hexadecanoyloxy)methyl‐ and 1‐<i>O</i>‐hexadecanoyl‐inositols as potential inhibitors of phospholipase C

D. James, R. Massy, Pierre C. Wyss · Helvetica Chimica Acta · 1990 · 46 citations

Bioorganic Chemistry, Organic Chemistry, Chemical Biology +16

1,3-Disubstituted 4-aminopiperidines as useful tools in the optimization of the 2-aminobenzo[a]quinolizine dipeptidyl peptidase IV inhibitors

Thomas Lübbers, Markus Böhringer, Luca Gobbi et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 34 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +10

Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity

Jean‐Philippe Surivet, Roland Lange, Christian Hubschwerlen et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 34 citations · Full text

Medicinal Chemistry, Vivo Anti-staphylococcal Activity, Natural Sciences +10

Synthesis of Heparin Saccharides IV. Synthesis of disaccharides possessing the structure of a repeating unit of heparin

Pierre C. Wyss, Joseph E. Kiss, Wolf Arnold · Helvetica Chimica Acta · 1975 · 31 citations

Biosynthesis, Bioorganic Chemistry, Engineering +10