Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

Haiying Zhang, Daniela Freitas, Han Sang Kim, +39

Nature Cell Biology

NanoparticlesExtracellular VesiclesEngineeringMedicineField-flow Fractionation +9

Age-induced accumulation of methylmalonic acid promotes tumour progression

Ana P. Gomes, Didem Ilter, Vivien Low, +18

Nature

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ

Shaobo Jin, Anders P. Mutvei, Indira Chivukula, +13

Oncogene

ImmunologyImmune RegulationCancer BiologyTumor BiologyInflammation +20

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms

Sebastian K.-J. Landor, Anders P. Mutvei, Veronika Mamaeva, +7

Proceedings of the National Academy of Sciences

Distinct MechanismsGlycobiologyMetabolic RemodelingAggressive Tumor GrowthCellular Physiology +22

Altered propionate metabolism contributes to tumour progression and aggressiveness

Ana P. Gomes, Didem Ilter, Vivien Low, +15

Nature Metabolism

Tumor BiologyMetabolic ReprogrammingMedicinePathologyCancer Metabolism +4

Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

Ana P. Gomes, Didem Ilter, Vivien Low, +20

Cancer Cell

Histone ModificationsChromatinDynamic IncorporationDevelopmental BiologyChromatin Remodeling +12

Control of Notch-ligand endocytosis by ligand-receptor interaction

Emil M. Hansson, Fredrik Lanner, Debashish Das, +8

Journal of Cell Science

Notch LigandsSignal TransductionSignaling PathwayMedicineCell Interaction +12

Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability

Anders P. Mutvei, Michal J. Nagiec, Jens C. Hamann, +3

Nature Communications

Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer

Linda Bojmar, Constantinos P. Zambirinis, Jonathan M. Hernandez, +71

Nature Medicine

Pre-metastatic LiverSurgical OncologyPancreatic CancerHepatologyMedicine +7

PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner

Marika Sjöqvist, Daniel Antfolk, Saima E. Ferraris, +9

Cell Research

Signal TransductionMolecular PhysiologySignaling PathwayNotch ReceptorCell Regulation +7