George D. Mcilroy

Expression of the yeast NADH dehydrogenase Ndi1 in <i>Drosophila</i> confers increased lifespan independently of dietary restriction

Alberto Sanz, Mikko Soikkeli, Manuel Portero-Otı́n et al. · Proceedings of the National Academy of Sciences · 2010 · 146 citations · Full text

Genetics, Molecular Genetics, Caloric Restriction +18

Susceptibility to diet-induced obesity and glucose intolerance in the APP SWE/PSEN1 A246E mouse model of Alzheimer’s disease is associated with increased brain levels of protein tyrosine phosphatase 1B (PTP1B) and retinol-binding protein 4 (RBP4), and basal phosphorylation of S6 ribosomal protein

Nimesh Mody, Abdelali Agouni, George D. Mcilroy et al. · Diabetologia · 2011 · 81 citations · Full text

Obesity, Metabolic Syndrome, Neurodegenerative Diseases +15

Fenretinide Treatment Prevents Diet-Induced Obesity in Association With Major Alterations in Retinoid Homeostatic Gene Expression in Adipose, Liver, and Hypothalamus

George D. Mcilroy, Mirela Delibegović, Carl Owen et al. · Diabetes · 2012 · 68 citations · Full text

Retinoic Acid, Metabolic Remodeling, Caloric Restriction +21

Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis

Carl Owen, Alicja Czopek, Abdelali Agouni et al. · PLoS ONE · 2012 · 64 citations · Full text

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

George D. Mcilroy, Karla J. Suchacki, Anke J. Roelofs et al. · Molecular Metabolism · 2018 · 44 citations · Full text