Julianna S. Deakyne

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

Troy E. Messick, Garry R. Smith, Samantha S. Soldan et al. · Science Translational Medicine · 2019 · 124 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes

Yuliang Wu, Joshua A. Sommers, Avvaru N. Suhasini et al. · Blood · 2010 · 73 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Cell-cycle-dependent EBNA1-DNA crosslinking promotes replication termination at oriP and viral episome maintenance

Jayaraju Dheekollu, Andreas Wiedmer, Kasirajan Ayyanathan et al. · Cell · 2021 · 62 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein–Barr virus-associated gastric cancer

Samantha S. Soldan, Emma M. Anderson, Drew Frase et al. · Gastric Cancer · 2021 · 35 citations · Full text

Medicine, Cancer Biology, Oncology +10

Polarity and Bypass of DNA Heterology during Branch Migration of Holliday Junctions by Human RAD54, BLM, and RECQ1 Proteins

Olga M. Mazina, Matthew J. Rossi, Julianna S. Deakyne et al. · Journal of Biological Chemistry · 2012 · 33 citations · Full text

Life Sciences, Genetics, Molecular Biology +16