Brenda Ames

Anti-Clumping Factor A Immunoglobulin Reduces the Duration of Methicillin-Resistant<i>Staphylococcus aureus</i>Bacteremia in an Experimental Model of Infective Endocarditis

John Vernachio, Arnold S. Bayer, Thuan Le et al. · Antimicrobial Agents and Chemotherapy · 2003 · 101 citations · Full text

Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus

Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 99 citations

Hepatology, Hepatitis C Virus, Viral Hepatitis +9

INX-08189, a Phosphoramidate Prodrug of 6-<i>O</i>-Methyl-2′-<i>C</i>-Methyl Guanosine, Is a Potent Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic and Pharmacodynamic Properties

John Vernachio, Blair Bleiman, K. Dawn Bryant et al. · Antimicrobial Agents and Chemotherapy · 2011 · 84 citations · Full text

Human Immunoglobulin G Recognizing Fibrinogen-Binding Surface Proteins Is Protective against both <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i> Infections In Vivo

John Vernachio, Arnold S. Bayer, Brenda Ames et al. · Antimicrobial Agents and Chemotherapy · 2006 · 68 citations · Full text

Phosphoramidate ProTides of 2′-<i>C</i>-Methylguanosine as Highly Potent Inhibitors of Hepatitis C Virus. Study of Their in Vitro and in Vivo Properties

Christopher McGuigan, Arnaud Gilles, Karolina Madela et al. · Journal of Medicinal Chemistry · 2010 · 56 citations