John Vernachio

Characterization of a Protective Monoclonal AntibodyRecognizing <i>Staphylococcus aureus</i> MSCRAMM ProteinClumping FactorA

Andrea Hall, Paul Domanski, Pratiksha Patel et al. · Infection and Immunity · 2003 · 145 citations · Full text

Life Sciences, Immunology, Microbiology +17

Inhibition of Complement Activation by a Secreted<i>Staphylococcus aureus</i>Protein

Lawrence Y. Lee, Magnus Höök, David L. Haviland et al. · The Journal of Infectious Diseases · 2004 · 135 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Anti-Clumping Factor A Immunoglobulin Reduces the Duration of Methicillin-Resistant<i>Staphylococcus aureus</i>Bacteremia in an Experimental Model of Infective Endocarditis

John Vernachio, Arnold S. Bayer, Thuan Le et al. · Antimicrobial Agents and Chemotherapy · 2003 · 102 citations · Full text

Pharmacy, Infectious Diseases, Microbiology +17

Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus

Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 99 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

INX-08189, a Phosphoramidate Prodrug of 6-<i>O</i>-Methyl-2′-<i>C</i>-Methyl Guanosine, Is a Potent Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic and Pharmacodynamic Properties

John Vernachio, Blair Bleiman, K. Dawn Bryant et al. · Antimicrobial Agents and Chemotherapy · 2011 · 84 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17