Grant R. Zimmermann

Synergistic drug combinations tend to improve therapeutically relevant selectivity

Joseph Lehár, Andrew Krueger, William Avery et al. · Nature Biotechnology · 2009 · 957 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +13

Systematic discovery of multicomponent therapeutics

Alexis A. Borisy, Peter J. Elliott, Nicole W. Hurst et al. · Proceedings of the National Academy of Sciences · 2003 · 631 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Chemical combination effects predict connectivity in biological systems

Joseph Lehár, Grant R. Zimmermann, Andrew Krueger et al. · Molecular Systems Biology · 2007 · 290 citations · Full text

Life Sciences, Systems Biology, Computational Biology +12

Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA

Grant R. Zimmermann, Robert Jenison, Catherine L. Wick et al. · Nature Structural Biology · 1997 · 284 citations

Life Sciences, Molecular Biology, Molecular Biophysics +15

Solution Structure of Bovine Neutrophil .beta.-Defensin-12: The Peptide Fold of the .beta.-Defensins Is Identical to That of the Classical Defensins

Grant R. Zimmermann, Pascale Legault, Michael E. Selsted et al. · Biochemistry · 1995 · 143 citations

Life Sciences, Biochemistry, Molecular Biology +12