Alexis A. Borisy

Synergistic drug combinations tend to improve therapeutically relevant selectivity

Joseph Lehár, Andrew Krueger, William Avery et al. · Nature Biotechnology · 2009 · 957 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +13

Systematic discovery of multicomponent therapeutics

Alexis A. Borisy, Peter J. Elliott, Nicole W. Hurst et al. · Proceedings of the National Academy of Sciences · 2003 · 631 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Chemical combination effects predict connectivity in biological systems

Joseph Lehár, Grant R. Zimmermann, Andrew Krueger et al. · Molecular Systems Biology · 2007 · 290 citations · Full text

Life Sciences, Systems Biology, Computational Biology +12

The Novel Combination of Chlorpromazine and Pentamidine Exerts Synergistic Antiproliferative Effects through Dual Mitotic Action

Margaret Lee, Lisa M. Johansen, Yanzhen Zhang et al. · Cancer Research · 2007 · 112 citations

Medicine, Oncology, Pharmacology +17

High‐order combination effects and biological robustness

Joseph Lehár, Andrew Krueger, Grant R. Zimmermann et al. · Molecular Systems Biology · 2008 · 97 citations · Full text

Engineering, Bioengineering, Biology +12