Lindsay A. Broadfield

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

James Lally, Sarani Ghoshal, Danielle K. DePeralta et al. · Cell Metabolism · 2018 · 395 citations · Full text

Oxysterol, Biochemistry, Medicine +8

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

Linda A. Villani, Brennan K. Smith, Katarina Marcinko et al. · Molecular Metabolism · 2016 · 229 citations · Full text

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

Matteo Rossi, Patricia Altea‐Manzano, Margherita Demicco et al. · Nature · 2022 · 200 citations · Full text

Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis

Lindsay A. Broadfield, João Duarte, Roberta Schmieder et al. · Cancer Research · 2021 · 95 citations · Full text

Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells <i>ex vivo</i> through inhibition of <i>de novo</i> lipogenesis

Andrew O’Brien, Linda A. Villani, Lindsay A. Broadfield et al. · Biochemical Journal · 2015 · 87 citations

Chemoprevention Strategy, Ampk β1, Cellular Pharmacology +21