Lindsay A. Broadfield

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

James Lally, Sarani Ghoshal, Danielle K. DePeralta et al. · Cell Metabolism · 2018 · 409 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

Linda A. Villani, Brennan K. Smith, Katarina Marcinko et al. · Molecular Metabolism · 2016 · 244 citations · Full text

Medicine, Oncology, Pharmacology +17

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

Matteo Rossi, Patricia Altea‐Manzano, Margherita Demicco et al. · Nature · 2022 · 210 citations · Full text

Medicine, Cancer Biology, Oncology +14

Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis

Lindsay A. Broadfield, João Duarte, Roberta Schmieder et al. · Cancer Research · 2021 · 95 citations · Full text

Life Sciences, Biochemistry, Cancer Biology +17

Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells <i>ex vivo</i> through inhibition of <i>de novo</i> lipogenesis

Andrew O’Brien, Linda A. Villani, Lindsay A. Broadfield et al. · Biochemical Journal · 2015 · 87 citations

Medicine, Oncology, Pharmacology +13