Andrew Mancini

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Robert J.A. Bell, H. Tomas Rube, Alex Kreig et al. · Science · 2015 · 573 citations · Full text

Life Sciences, Genetics, Oncology +17

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

Andrew Mancini, Ana Xavier‐Magalhães, Wendy S. Woods et al. · Cancer Cell · 2018 · 149 citations · Full text

Medicine, Molecular Biology, Oncology +14

Mutant IDH1 Expression Drives <i>TERT</i> Promoter Reactivation as Part of the Cellular Transformation Process

Shigeo Ohba, Joydeep Mukherjee, Tor-Christian Aase Johannessen et al. · Cancer Research · 2016 · 61 citations

Life Sciences, Genetics, Oncology +17

Cancer-specific loss of <i>TERT</i> activation sensitizes glioblastoma to DNA damage

Alexandra M. Amen, Christof Fellmann, Katarzyna M. Soczek et al. · Proceedings of the National Academy of Sciences · 2021 · 51 citations · Full text

Medicine, Cancer Biology, Oncology +17

Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis

Antonina V. Kurtova, Melanie Heinlein, Simon Haas et al. · Blood Advances · 2022 · 31 citations · Full text

Life Sciences, Cell Biology, Hematology +17