H. Tomas Rube

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Robert J.A. Bell, H. Tomas Rube, Alex Kreig et al. · Science · 2015 · 573 citations · Full text

Life Sciences, Genetics, Oncology +17

AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

Liyang Zhang, John A. Zuris, Ramya Viswanathan et al. · Nature Communications · 2021 · 172 citations · Full text

Life Sciences, Biotechnology, Oncology +15

Measuring DNA mechanics on the genome scale

Aakash Basu, Dmitriy G. Bobrovnikov, Zan Qureshi et al. · Nature · 2020 · 164 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning

H. Tomas Rube, Chaitanya Rastogi, Siqian Feng et al. · Nature Biotechnology · 2022 · 134 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Accurate and sensitive quantification of protein-DNA binding affinity

Chaitanya Rastogi, H. Tomas Rube, Judith F. Kribelbauer et al. · Proceedings of the National Academy of Sciences · 2018 · 129 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +15