Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy

Magali Noval Rivas, Oliver T. Burton, Petra M. Wise, +5

Immunity

AllergyT-regulatory CellImmunologyRegulatory T CellsPromotes Food Allergy +6

Cancer-Associated Fibroblasts Promote Immunosuppression by Inducing ROS-Generating Monocytic MDSCs in Lung Squamous Cell Carcinoma

Handan Xiang, Carlo P. Ramil, Josephine Hai, +16

Cancer Immunology Research

Oncometabolite <scp>d</scp> -2HG alters T cell metabolism to impair CD8 ⁺ T cell function

Giulia Notarangelo, Jessica B. Spinelli, Elizabeth M. Perez, +21

Science

MyD88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces Commensalism

Sen Wang, Louis‐Marie Charbonnier, Magali Noval Rivas, +5

Immunity

InflammationMucosal ImmunologyMicrobial PathogensT-regulatory CellImmunology +7

Control of peripheral tolerance by regulatory T cell–intrinsic Notch signaling

Louis‐Marie Charbonnier, Sen Wang, Peter Georgiev, +2

Nature Immunology

Signal TransductionT-regulatory CellImmune RegulationImmunologyRegulatory T Cells +12

A2B Adenosine Receptor Blockade Enhances Macrophage-Mediated Bacterial Phagocytosis and Improves Polymicrobial Sepsis Survival in Mice

Bryan Belikoff, Stephen Hatfield, Peter Georgiev, +5

The Journal of Immunology

InflammationCytokineA2br Knockout MiceMicrobial PathogensLung Inflammation +11

IL-10 Produced by Induced Regulatory T Cells (iTregs) Controls Colitis and Pathogenic Ex-iTregs during Immunotherapy

Erica G. Schmitt, Dipica Haribhai, Jason B. Williams, +14

The Journal of Immunology

Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells

Selvakumar Sukumar, Douglas C. Wilson, Ying Yu, +19

Cancer Research

Combination of EP ₄ antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells

Yun Wang, Long Cui, Peter Georgiev, +25

OncoImmunology

Pharmacological inhibition of hematopoietic progenitor kinase 1 positively regulates T-cell function

Yun Wang, Kelvin Zhang, Peter Georgiev, +10

PLoS ONE