Cancer-Associated Fibroblasts Promote Immunosuppression by Inducing ROS-Generating Monocytic MDSCs in Lung Squamous Cell Carcinoma

Handan Xiang, Carlo P. Ramil, Josephine Hai, +16

Cancer Immunology Research

Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis

T Liu, Rigel J. Kishton, Andrew N. Macintyre, +7

Cell Death and Disease

Mixed-phenotype Acute LeukemiaImmunologyCell DeathMetabolic RemodelingTumor Biology +19

<scp>CD</scp> 36 initiates the secretory phenotype during the establishment of cellular senescence

Mengyang Chong, Tao Yin, Rui Chen, +8

EMBO Reports

Developmental BiologySignal TransductionCell RegulationSecretory PhenotypeCellular Senescence +5

Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death

Lifeng Yuan, Linhui Zhai, Lili Qian, +12

Cell Research

Signal TransductionCell RegulationLongevityApoptosisCell Death +8

Single-Cell Analysis Identifies NOTCH3-Mediated Interactions between Stromal Cells That Promote Microenvironment Remodeling and Invasion in Lung Adenocarcinoma

Handan Xiang, Yidan Pan, Marc A. Sze, +26

Cancer Research

UHRF1 is required for basal stem cell proliferation in response to airway injury

Handan Xiang, Lifeng Yuan, Xia Gao, +13

Cell Discovery

Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers

Yi Ding, Chang Gong, De Huang, +14

Nature Communications

Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response

Lianmei Tan, Tao Yin, Handan Xiang, +17

Nature Communications

Extracellular vesicles released by cancer-associated fibroblast-induced myeloid-derived suppressor cells inhibit T-cell function

Carlo P. Ramil, Handan Xiang, Peng Zhang, +10

OncoImmunology