Concepedia

Brett A. Howell

BA

29

Publications

1.1K

Citations

19

H-Index

2007

Active since

Affiliations

University of North Carolina at Chapel Hill(Current)

Research Triangle Park Foundation

University of Florida

Triangle

Simulations Plus (United States)

Brett A. Howell is an author at University of North Carolina at Chapel Hill specializing in medicine, pharmacology, and hepatology.

ORCID

Top concepts

Publications per year

2007–2023

29

Publications

29

In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI

Brett A. Howell, Yuching Yang, Rukmini Kumar et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2012 · 105 citations

, , +12

Exploring BSEP inhibition-mediated toxicity with a mechanistic model of drug-induced liver injury

Jeffrey L. Woodhead, Kyunghee Yang, Scott Q. Siler et al. · Frontiers in Pharmacology · 2014 · 92 citations · Full text

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors

Jeffrey L. Woodhead, William J. Brock, Sharin E. Roth et al. · Toxicological Sciences · 2016 · 89 citations · Full text

, , +20

An Analysis of N-Acetylcysteine Treatment for Acetaminophen Overdose Using a Systems Model of Drug-Induced Liver Injury

Jeffrey L. Woodhead, Brett A. Howell, Yuching Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 79 citations

Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling

Jeffrey L. Woodhead, Kyunghee Yang, David Oldach et al. · Pharmaceutical Research · 2019 · 63 citations · Full text

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