Stefan Freigang

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection

Mai Matsushita, Stefan Freigang, Christoph Schneider et al. · The Journal of Experimental Medicine · 2015 · 628 citations · Full text

Adaptive Immune System, T-regulatory Cell, Lipid Peroxidation +27

IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection

Anja Fröhlich, Jan Kisielow, Iwana Schmitz et al. · Science · 2009 · 445 citations

Autoimmune Disease, T Cells, T-regulatory Cell +14

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

Karl S. Lang, Mike Recher, Tobias Junt et al. · Nature Medicine · 2005 · 370 citations · Full text

Inflammation, Toll-like Receptors, Autoimmune Disease +10

Immunization of LDL Receptor–Deficient Mice With Homologous Malondialdehyde-Modified and Native LDL Reduces Progression of Atherosclerosis by Mechanisms Other Than Induction of High Titers of Antibodies to Oxidative Neoepitopes

Stefan Freigang, Sohvi Hörkkö, Elizabeth R. Miller et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 319 citations

Vascular Disease, Lipid Peroxidation, Immunology +20

Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis

Stefan Freigang, Franziska Ampenberger, Adrienne Weiss et al. · Nature Immunology · 2013 · 300 citations

Inflammation, Metabolic Syndrome, Mitochondrial Function +11