Frank J. Bruggeman

Untangling the wires: A strategy to trace functional interactions in signaling and gene networks

Boris Ν. Kholodenko, Anatoly Kiyatkin, Frank J. Bruggeman et al. · Proceedings of the National Academy of Sciences · 2002 · 433 citations · Full text

Genetics, Molecular Biology, Network Analysis +21

Lost in Transition: Start-Up of Glycolysis Yields Subpopulations of Nongrowing Cells

Johan H. van Heerden, Meike T. Wortel, Frank J. Bruggeman et al. · Science · 2014 · 307 citations

Cell Cycle, Metabolic Remodeling, Cell Growth +22

How fast‐growing bacteria robustly tune their ribosome concentration to approximate growth‐rate maximization

Evert Bosdriesz, Douwe Molenaar, Bas Teusink et al. · FEBS Journal · 2015 · 261 citations · Full text

Engineering, Bacteriology, Molecular Biology +20

Community Flux Balance Analysis for Microbial Consortia at Balanced Growth

Ruchir A. Khandelwal, Brett G. Olivier, Wilfred F. M. Röling et al. · PLoS ONE · 2013 · 229 citations · Full text

Synthetic Ecology, Reaction Thermodynamics, Metabolic Model +17

Control of MAPK signalling: from complexity to what really matters

Jorrit J. Hornberg, Bernd R. Binder, Frank J. Bruggeman et al. · Oncogene · 2005 · 203 citations

Molecular Physiology, Signal Transduction, Signaling Pathway +10