Ryan J. Cecchi

Comparison of Cas9 activators in multiple species

Alejandro Chavez, Marcelle Tuttle, Benjamin W. Pruitt et al. · Nature Methods · 2016 · 553 citations · Full text

Life Sciences, Genetics, Molecular Biology +6

An enhanced CRISPR repressor for targeted mammalian gene regulation

Nan Cher Yeo, Alejandro Chavez, Alissa Lance‐Byrne et al. · Nature Methods · 2018 · 535 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast

Xiaoge Guo, Alejandro Chavez, Angela Tung et al. · Nature Biotechnology · 2018 · 107 citations

Life Sciences, Genetics, Molecular Biology +17

Mimicking the tumor microenvironment to regulate macrophage phenotype and assessing chemotherapeutic efficacy in embedded cancer cell/macrophage spheroid models

Kristie M. Tevis, Ryan J. Cecchi, Yolonda L. Colson et al. · Acta Biomaterialia · 2016 · 73 citations

Medicine, Cancer Biology, Oncology +17

Precise Cas9 targeting enables genomic mutation prevention

Alejandro Chavez, Benjamin W. Pruitt, Marcelle Tuttle et al. · Proceedings of the National Academy of Sciences · 2018 · 33 citations · Full text

Life Sciences, Genetics, Molecular Biology +15