Mohammed L. Ibrahim

An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion

John D. Klement, Amy V. Paschall, Priscilla S. Redd et al. · Journal of Clinical Investigation · 2018 · 373 citations · Full text

Life Sciences, Immunology, Oncology +17

Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes

Chunwan Lu, John D. Klement, Mohammed L. Ibrahim et al. · Journal for ImmunoTherapy of Cancer · 2019 · 143 citations · Full text

Medicine, Immunology, Oncology +13

Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis

Mohammed L. Ibrahim, John D. Klement, Chunwan Lu et al. · Cell Reports · 2018 · 130 citations · Full text

Medicine, Immunology, Oncology +17

IFNAR1 Controls Autocrine Type I IFN Regulation of PD-L1 Expression in Myeloid-Derived Suppressor Cells

Wei Xiao, John D. Klement, Chunwan Lu et al. · The Journal of Immunology · 2018 · 92 citations · Full text

Medicine, Immunology, Oncology +17

Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells

Alyssa D. Smith, Chunwan Lu, Daniela Payne et al. · Cancer Research · 2020 · 76 citations · Full text

Medicine, Cancer Biology, Oncology +17