Buelent Koçer

DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

Hans Richter, Alexander L. Satz, Marc Bedoucha et al. · ACS Chemical Biology · 2018 · 113 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis

Yan Lou, Xiaochun Han, A. Kuglstatter et al. · Journal of Medicinal Chemistry · 2014 · 108 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of carmegliptin: A potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

Patrizio Mattei, Markus Boehringer, Patrick Di Giorgio et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery and Pre-Clinical Characterization of Third-Generation 4-H Heteroaryldihydropyrimidine (HAP) Analogues as Hepatitis B Virus (HBV) Capsid Inhibitors

Zongxing Qiu, Xianfeng Lin, Weixing Zhang et al. · Journal of Medicinal Chemistry · 2017 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton’s Tyrosine Kinase (BTK) inhibitor scaffold

Yan Lou, Zachary K. Sweeney, A. Kuglstatter et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13