Elizabeth A. Giuliani

Selective Inhibition of <i>ras</i> -Dependent Transformation by a Farnesyltransferase Inhibitor

Nancy E. Kohl, Scott D. Mosser, S. J. DESOLMS et al. · Science · 1993 · 579 citations

Molecular Biology, Chemical Biology, Ras Processing +17

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

Nancy E. Kohl, Charles A. Omer, Michael W. Conner et al. · Nature Medicine · 1995 · 538 citations

Farnesyltransferase Induces Regression, Tumor Biology, Chemoprevention Strategy +12

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice.

Nancy E. Kohl, Francine R. Wilson, S D Mosser et al. · Proceedings of the National Academy of Sciences · 1994 · 286 citations · Full text

Pathology, Cancer Biology, Tumor Biology +17

Farnesyltransferase Inhibition Causes Morphological Reversion of <i>ras</i> -Transformed Cells by a Complex Mechanism That Involves Regulation of the Actin Cytoskeleton

George C. Prendergast, Joseph P. Da Vide, S. J. DESOLMS et al. · Molecular and Cellular Biology · 1994 · 194 citations · Full text

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton.

George C. Prendergast, Joseph P. Davide, S. J. DESOLMS et al. · Molecular and Cellular Biology · 1994 · 146 citations

Molecular Regulation, Farnesyltransferase Inhibition, Cell Proliferation +20