Jens Sydor

Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926)

Martin Tremblay, André Lescarbeau, Michael J. Grogan et al. · Journal of Medicinal Chemistry · 2009 · 250 citations · Full text

Medicinal Chemistry, Compound 28, Pharmaceutical Science +13

Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90

Jens Sydor, Emmanuel Normant, Christine Pien et al. · Proceedings of the National Academy of Sciences · 2006 · 226 citations · Full text

Tumor Biology, Medicinal Chemistry, Medicine +13

Design, Synthesis, and Biological Evaluation of Hydroquinone Derivatives of 17-Amino-17-demethoxygeldanamycin as Potent, Water-Soluble Inhibitors of Hsp90

Jie Ge, Emmanuel Normant, James R. Porter et al. · Journal of Medicinal Chemistry · 2006 · 189 citations · Full text

Hydroquinone Derivatives, Medicinal Chemistry, Water-soluble Inhibitors +13

The Photophobic Receptor from Natronobacterium pharaonis: Temperature and pH Dependencies of the Photocycle of Sensory Rhodopsin II

Igor Chizhov, Georg Schmies, R. Seidel et al. · Biophysical Journal · 1998 · 172 citations · Full text

Photophobic Receptor, Photoreceptor Cell, Biochemistry +9

Transient Kinetic Studies on the Interaction of Ras and the Ras-Binding Domain of c-Raf-1 Reveal Rapid Equilibration of the Complex

Jens Sydor, Martin Engelhard, Alfred Wittinghofer et al. · Biochemistry · 1998 · 128 citations