Lay T. Gan

NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications

Geoffrey C. Farrell, Derrick van Rooyen, Lay T. Gan et al. · Gut and Liver · 2012 · 395 citations · Full text

Medicine, Pathobiology, Pathology +17

Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent

Lay T. Gan, Derrick M. Van Rooyen, Mark E. Koina et al. · Journal of Hepatology · 2014 · 199 citations

Life Sciences, Biochemistry, Cell Biology +14

Mechanisms and Implications of Age-Related Changes in the Liver: Nonalcoholic Fatty Liver Disease in the Elderly

Lay T. Gan, Shivakumar Chitturi, Geoffrey C. Farrell · Current Gerontology and Geriatrics Research · 2011 · 138 citations · Full text

Medicine, Geriatric Medicine, Pathology +17

Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome

Derrick M. Van Rooyen, Lay T. Gan, Matthew M. Yeh et al. · Journal of Hepatology · 2013 · 123 citations

Medicine, Biochemistry, Pharmacology +17

Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia

Jessica Bruce, Grace L. Burns, Wai Sinn Soh et al. · Brain Behavior and Immunity · 2022 · 34 citations

Life Sciences, Cell Biology, Molecular Biology +13