Yuka A. Martens

APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

Jing Zhao, Yuan Fu, Yu Yamazaki et al. · Nature Communications · 2020 · 352 citations · Full text

Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes

Na Zhao, Chia‐Chen Liu, Alexandra J. Van Ingelgom et al. · Neuron · 2017 · 275 citations · Full text

Metabolic Syndrome, Signal Transduction, Molecular Physiology +8

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

Li Zhong, Zongqi Wang, Daxin Wang et al. · Molecular Neurodegeneration · 2018 · 249 citations · Full text

Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways

Na Zhao, Yingxue Ren, Yu Yamazaki et al. · Neuron · 2020 · 246 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Aging +11

APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes

Jing Zhao, Mary Dabney Davis, Yuka A. Martens et al. · Human Molecular Genetics · 2017 · 212 citations · Full text

Brain Development, Neurochemical Biomarkers, Social Sciences +23