Darren McKerrecher

Unexpected reactivity of two-coordinate palladium–carbene complexes; synthetic and catalytic implications

Lisa Titcomb, Stephen Caddick, F. Geoffrey N. Cloke et al. · Chemical Communications · 2001 · 160 citations

Inorganic Chemistry, Chemical Engineering, Unexpected Lability +10

Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions

Nicolas Floc’h, Matthew J. Martin, Jonathan W. Riess et al. · Molecular Cancer Therapeutics · 2018 · 110 citations · Full text

The First Example of Simple Oxidative Addition of an Aryl Chloride to a Discrete Palladium N-Heterocyclic Carbene Amination Precatalyst

Stephen Caddick, F. Geoffrey N. Cloke, Peter B. Hitchcock et al. · Organometallics · 2002 · 100 citations

Inorganic Chemistry, Chemical Engineering, Arylated Imidazolium Salt +14

An improved synthesis of bis(1,3-di-N-tert-butylimidazol-2-ylidene)palladium(0) and its use in C–C and C–N coupling reactions

Stephen Caddick, F. Geoffrey N. Cloke, G.K.B. Clentsmith et al. · Journal of Organometallic Chemistry · 2001 · 95 citations

Cross-coupling Reaction, Improved Synthesis, Organometallic Catalysis +3

Design of a potent, soluble glucokinase activator with excellent in vivo efficacy

Darren McKerrecher, Joanne V. Allen, Peter W. R. Caulkett et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 84 citations · Full text

Medicine, Drug Discovery, Glycobiology +6