Paola Nicoletti

The support of human genetic evidence for approved drug indications

Matthew R. Nelson, Hannah Tipney, Jeffery L. Painter et al. · Nature Genetics · 2015 · 1.8K citations

Medicine, Genetics, Molecular Genetics +10

Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

Andrew Grant, Graeme S. Cottrell, Silvia Amadesi et al. · The Journal of Physiology · 2006 · 388 citations · Full text

Life Sciences, Molecular Biology, Neurobiology +17

Elucidating Compound Mechanism of Action by Network Perturbation Analysis

Jung Hoon Woo, Yishai Shimoni, Wan Seok Yang et al. · Cell · 2015 · 353 citations · Full text

Life Sciences, Chemistry, Medicinal Chemistry +14

Rare Deletions at 16p13.11 Predispose to a Diverse Spectrum of Sporadic Epilepsy Syndromes

Erin L. Heinzen, Rodney A. Radtke, Thomas Urban et al. · The American Journal of Human Genetics · 2010 · 259 citations · Full text

Medicine, Genetics, Molecular Genetics +17

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

Paola Nicoletti, Guruprasad P. Aithal, Einar S. Björnsson et al. · Gastroenterology · 2016 · 221 citations · Full text

Life Sciences, Genetics, Pharmacology +13