Graeme S. Cottrell

Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome

Giovanni Barbara, Vincenzo Stanghellini, Roberto De Giorgio et al. · Gastroenterology · 2004 · 1.4K citations

Inflammation, Functional Gastrointestinal Disorder, Allergy +11

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

Marcello Trevisani, Jan Siemens, Serena Materazzi et al. · Proceedings of the National Academy of Sciences · 2007 · 753 citations · Full text

Pain Medicine, Immunology, Neuropathic Pain +22

Role for protease activity in visceral pain in irritable bowel syndrome

Nicolas Cénac, Christopher N. Andrews, Marinella Holzhausen et al. · Journal of Clinical Investigation · 2007 · 577 citations · Full text

Pain Medicine, Immunology, Gastroenterology +17

Protease-Activated Receptor 2 Sensitizes the Capsaicin Receptor Transient Receptor Potential Vanilloid Receptor 1 to Induce Hyperalgesia

Silvia Amadesi, Jingjiang Nie, Nathalie Vergnolle et al. · Journal of Neuroscience · 2004 · 403 citations · Full text

Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

Andrew Grant, Graeme S. Cottrell, Silvia Amadesi et al. · The Journal of Physiology · 2006 · 384 citations · Full text