Si Cheng

Trimethylamine‐<i>N</i>‐oxide promotes brain aging and cognitive impairment in mice

Li Dang, Yilang Ke, Rui Zhan et al. · Aging Cell · 2018 · 287 citations · Full text

Aging, Host-microbe Interactions, Gut Microbiota +17

Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress

Yilang Ke, Li Dang, Mingming Zhao et al. · Free Radical Biology and Medicine · 2018 · 279 citations

Lifespan Extension, Aging, Longevity +10

TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice

Mingming Zhao, Lin Zhao, Xuelian Xiong et al. · Gastroenterology · 2020 · 125 citations

Inflammation, Intestinal Microbes, Hepatology +14

Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy

Mingming Zhao, Haoran Wei, Chenze Li et al. · Nature Communications · 2022 · 94 citations · Full text

Telmisartan Ameliorates Nephropathy in Metabolic Syndrome by Reducing Leptin Release From Perirenal Adipose Tissue

Hao Li, Min Li, Ping Liu et al. · Hypertension · 2016 · 62 citations · Full text

Renal Inflammation, Adipokines, Prat-derived Leptin +23