Si Cheng

Trimethylamine‐<i>N</i>‐oxide promotes brain aging and cognitive impairment in mice

Li Dang, Yilang Ke, Rui Zhan et al. · Aging Cell · 2018 · 297 citations · Full text

Education, Neurobiology, Pharmacology +17

Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress

Yilang Ke, Li Dang, Mingming Zhao et al. · Free Radical Biology and Medicine · 2018 · 290 citations

Life Sciences, Nutritional Sciences, Pharmacology +12

TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice

Mingming Zhao, Lin Zhao, Xuelian Xiong et al. · Gastroenterology · 2020 · 130 citations

Life Sciences, Biochemistry, Microbiology +17

Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy

Mingming Zhao, Haoran Wei, Chenze Li et al. · Nature Communications · 2022 · 102 citations · Full text

Life Sciences, Cardiology, Microbiology +16

The STROMICS genome study: deep whole-genome sequencing and analysis of 10K Chinese patients with ischemic stroke reveal complex genetic and phenotypic interplay

Si Cheng, Zhe Xu, Shengzhe Bian et al. · Cell Discovery · 2023 · 69 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15