JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia

Andrea Bonetto, Tufan Aydogdu, Xiaoling Jin, +5

American Journal of Physiology-Endocrinology and Metabolism

ImmunologyCell DeathCellular PhysiologyInflammationSignaling Pathway +14

Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

Eiji Furuta, Sudha K. Pai, Rui Zhan, +13

Cancer Research

Trimethylamine‐<i>N</i>‐oxide promotes brain aging and cognitive impairment in mice

Li Dang, Yilang Ke, Rui Zhan, +9

Aging Cell

AgingHost-microbe InteractionsGut MicrobiotaBiogerontologyOxidative Stress +15

Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression

Sucharita Bandyopadhyay, Rui Zhan, Asok Chaudhuri, +16

Nature Medicine

Tumor BiologyAngiogenesisMalignant DiseaseMedicineCell Death +10

Mechanism of Apoptosis Induced by the Inhibition of Fatty Acid Synthase in Breast Cancer Cells

Sucharita Bandyopadhyay, Rui Zhan, Ying Wang, +11

Cancer Research

Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection

Hongtu Cui, Yanghui Chen, Ke Li, +18

European Heart Journal

Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes

Rui Zhan, Xue Leng, Xiaohua Liu, +7

Biochemical and Biophysical Research Communications

Protein SecretionProtein FunctionSignal TransductionEndothelial CellsNon-classical Pathway +11

The Tumor Metastasis Suppressor Gene <i>Drg-1</i> Down-regulates the Expression of Activating Transcription Factor 3 in Prostate Cancer

Sucharita Bandyopadhyay, Ying Wang, Rui Zhan, +16

Cancer Research

Transcriptional RegulationCell RegulationMedicineDrg-1 ExpressionCancer Cell Biology +8

The Attenuation of Diabetic Nephropathy by Annexin A1 via Regulation of Lipid Metabolism Through the AMPK/PPARα/CPT1b Pathway

Liang Wu, Changjie Liu, Dong‐Yuan Chang, +7

Diabetes

Annexin A1 alleviates kidney injury by promoting the resolution of inflammation in diabetic nephropathy

Liang Wu, Changjie Liu, Dong‐Yuan Chang, +16

Kidney International

InflammationGlomerulonephritisAnnexin A1Kidney InjuryRenal Function +13