Brian C. Gruber

Statistics

Publications

Citations

749

H-Index

Active since

2000

Affiliations

Women's Health Research Institute(Current)

Brian C. Gruber is an author at Women's Health Research Institute specializing in medicinal chemistry, epidermal growth factor receptor inhibition, and enzyme inhibition.

Publications per year

2000–2002

Publications

6-Substituted-4-(3-bromophenylamino)quinazolines as Putative Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor (HER-2) Tyrosine Kinases with Enhanced Antitumor Activity

Hwei‐Ru Tsou, Nellie Mamuya, Bernard D. Johnson et al. · Journal of Medicinal Chemistry · 2001 · 274 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Synthesis and Structure−Activity Relationships of 6,7-Disubstituted 4-Anilinoquinoline-3-carbonitriles. The Design of an Orally Active, Irreversible Inhibitor of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor (EGFR) and the Human Epidermal Growth Factor Receptor-2 (HER-2)

Allan Wissner, Elsebe Overbeek, Marvin F. Reich et al. · Journal of Medicinal Chemistry · 2002 · 266 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile Inhibitors of Epidermal Growth Factor Receptor Kinase and Their Bioisosteric Relationship to the 4-Anilino-6,7-dialkoxyquinazoline Inhibitors

Allan Wissner, Dan M. Berger, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 2000 · 209 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

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