The Synthetic Triterpenoids, CDDO and CDDO-Imidazolide, Are Potent Inducers of Heme Oxygenase-1 and Nrf2/ARE Signaling

Karen T. Liby, Thomas Hock, Mark M. Yore, +11

Cancer Research

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription

Lichuan Yang, Noel Y. Calingasan, Bobby Thomas, +11

PLoS ONE

Lipid PeroxidationCell DeathRedox BiologyOxidative StressNeuroinflammation +16

The Synthetic Triterpenoids CDDO-Methyl Ester and CDDO-Ethyl Amide Prevent Lung Cancer Induced by Vinyl Carbamate in A/J Mice

Karen T. Liby, Darlene B. Royce, Charlotte R. Williams, +7

Cancer Research

Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer

Ana S. Leal, Charlotte R. Williams, Darlene B. Royce, +3

Cancer Letters

Tumor BiologyPotential TherapiesPancreatic CancerBromodomain InhibitorsMedicine +5

The Synthetic Triterpenoid CDDO-Imidazolide Suppresses STAT Phosphorylation and Induces Apoptosis in Myeloma and Lung Cancer Cells

Karen T. Liby, Nga Voong, Charlotte R. Williams, +6

Clinical Cancer Research

Synthetic Triterpenoids Prolong Survival in a Transgenic Mouse Model of Pancreatic Cancer

Karen T. Liby, Darlene B. Royce, Renee Risingsong, +4

Cancer Prevention Research

OncologyPancreatic CancerKpc Transgenic MiceOncogenic AgentMedicine +10

Synthetic Triterpenoids Attenuate Cytotoxic Retinal Injury: Cross-talk between Nrf2 and PI3K/AKT Signaling through Inhibition of the Lipid Phosphatase PTEN

Ian Pitha, Karen T. Liby, Darlene B. Royce, +1

Investigative Ophthalmology & Visual Science

The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient Mice

Ciric To, Eun‐Hee Kim, Darlene B. Royce, +5

Cancer Prevention Research

Prevention and Treatment of Experimental Estrogen Receptor–Negative Mammary Carcinogenesis by the Synthetic Triterpenoid CDDO-Methyl Ester and the Rexinoid LG100268

Karen T. Liby, Renee Risingsong, Darlene B. Royce, +9

Clinical Cancer Research

Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis

Ciric To, Carol S. Ringelberg, Darlene B. Royce, +4

Carcinogenesis