Karen T. Liby

Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress

Albena T. Dinkova‐Kostova, Karen T. Liby, Katherine K. Stephenson et al. · Proceedings of the National Academy of Sciences · 2005 · 566 citations

Life Sciences, Immunology, Pharmacology +17

Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide

Rajesh K. Thimmulappa, Catherine Scollick, Kassim Traore et al. · Biochemical and Biophysical Research Communications · 2006 · 351 citations · Full text

Life Sciences, Immunology, Pharmacology +14

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

Thomas E. Sussan, Tirumalai Rangasamy, David J. Blake et al. · Proceedings of the National Academy of Sciences · 2008 · 346 citations · Full text

Life Sciences, Pathobiology, Pharmacology +17

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes

Melinda S. Yates, Masafumi Tauchi, Fumiki Katsuoka et al. · Molecular Cancer Therapeutics · 2007 · 293 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The Synthetic Triterpenoids, CDDO and CDDO-Imidazolide, Are Potent Inducers of Heme Oxygenase-1 and Nrf2/ARE Signaling

Karen T. Liby, Thomas Hock, Mark M. Yore et al. · Cancer Research · 2005 · 284 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16