The structural basis of direct glucocorticoid-mediated transrepression

William Henry Hudson, Christine Youn, Eric A. Ortlund

Nature Structural & Molecular Biology

Signal TransductionProtein ExpressionG Protein-coupled ReceptorCell SignalingNatural Sciences +7

Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease

Garrett J. Patrick, Haiyun Liu, Martin P. Alphonse, +34

Journal of Clinical Investigation

AsthmaInflammatory Lung DiseaseAllergy MedicineImmunologyImmune Regulation +21

Crystal Structure of the Mineralocorticoid Receptor DNA Binding Domain in Complex with DNA

William Henry Hudson, Christine Youn, Eric A. Ortlund

PLoS ONE

Crystal StructureEngineeringGeneticsMolecular BiologyGlucocorticoid +15

Enhanced Cell Growth of Adipocyte-Derived Mesenchymal Stem Cells Using Chemically-Defined Serum-Free Media

Myung‐Suk Lee, Christine Youn, Jeong Geun Kim, +6

International Journal of Molecular Sciences

Tissue EngineeringRegenerative MedicineMesenchymal Stem CellsEmbryonic Stem CellEngineering +13

Macrophages use a bet-hedging strategy for antimicrobial activity in phagolysosomal acidification

Quigly Dragotakes, Kaitlin Stouffer, Man Shun Fu, +7

Journal of Clinical Investigation

Bet HedgingPhysiologyImmunologyPh ValuesBacteriophage +12

Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections

Martin P. Alphonse, Jessica Rubens, Roger V. Ortines, +16

Science Translational Medicine

IL-6R/Signal Transducer and Activator of Transcription 3 Signaling in Keratinocytes rather than in T Cells Induces Psoriasis-Like Dermatitis in Mice

Advaitaa Ravipati, Sabrina Nolan, Martin P. Alphonse, +14

Journal of Investigative Dermatology

InflammationIl-6r/signal TransducerCutaneous BiologyImmunologyImmune Regulation +6

Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection

Xintong Dong, Nathachit Limjunyawong, Elizabeth I. Sypek, +17

Immunity

InflammationAutoimmune DiseaseNeutrophil-specific Receptors Mrgpra2a/bMedicineCutaneous Biology +6

IgG3 regulates tissue-like memory B cells in HIV-infected individuals

Lela Kardava, Haewon Sohn, Christine Youn, +15

Nature Immunology

Hiv-infected IndividualsHuman RetrovirusImmunologyAntiviral ResponseAutoimmunity +4

Research Techniques Made Simple: Mouse Bacterial Skin Infection Models for Immunity Research

Christine Youn, Nathan K. Archer, Lloyd Miller

Journal of Investigative Dermatology

Host ResponseResearch TechniquesMicrobial DiseaseImmunity ResearchPathogen Transmission +5