Eric A. Ortlund

Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients

Mehul S. Suthar, Matthew G. Zimmerman, Robert C. Kauffman et al. · Cell Reports Medicine · 2020 · 546 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +16

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Joel Blanchard, Leyla Anne Akay, José Dávila-Velderrain et al. · Nature · 2022 · 499 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Crystal Structure of an Ancient Protein: Evolution by Conformational Epistasis

Eric A. Ortlund, Jamie T. Bridgham, Matthew R. Redinbo et al. · Science · 2007 · 450 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

Jamie T. Bridgham, Eric A. Ortlund, Joseph W. Thornton · Nature · 2009 · 426 citations

Life Sciences, Evolutionary Biology, Molecular Genetics +12

Evolutionary history and metabolic insights of ancient mammalian uricases

James T. Kratzer, Miguel A. Lanaspa, Michael Murphy et al. · Proceedings of the National Academy of Sciences · 2014 · 351 citations · Full text

Life Sciences, Biochemistry, Evolutionary Biology +14