Eric A. Ortlund

Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients

Mehul S. Suthar, Matthew G. Zimmerman, Robert C. Kauffman et al. · Cell Reports Medicine · 2020 · 541 citations · Full text

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Joel Blanchard, Leyla Anne Akay, José Dávila-Velderrain et al. · Nature · 2022 · 460 citations · Full text

Oxysterol, Physiology, Degenerative Pathology +6

Crystal Structure of an Ancient Protein: Evolution by Conformational Epistasis

Eric A. Ortlund, Jamie T. Bridgham, Matthew R. Redinbo et al. · Science · 2007 · 440 citations · Full text

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

Jamie T. Bridgham, Eric A. Ortlund, Joseph W. Thornton · Nature · 2009 · 417 citations · Full text

Signal Transduction, Molecular Physiology, Developmental Biology +8

Evolutionary history and metabolic insights of ancient mammalian uricases

James T. Kratzer, Miguel A. Lanaspa, Michael Murphy et al. · Proceedings of the National Academy of Sciences · 2014 · 332 citations · Full text