Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation

Mario Hofweber, Saskia Hutten, Benjamin Bourgeois, +8

Cell

ChromatinNuclear Import ReceptorBiochemistryNatural SciencesEpigenetic Change +8

The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity

Fionna E. Loughlin, Peter J. Lukavsky, Tamara Kazeeva, +10

Molecular Cell

Systems BiologyEngineeringRna RecognitionRna Structure PredictionComputational Biology +9

FUS-dependent liquid–liquid phase separation is important for DNA repair initiation

Brunno Rocha Levone, Silvia C. Lenzken, Marco Antonaci, +11

The Journal of Cell Biology

ChromatinGenome InstabilityRna MetabolismChromatin RemodelingDna Repair Initiation +11

Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways

Stefanie Metze, Veronika A. Herzog, Marc‐David Ruepp, +1

RNA

Ejc-independent NmdMolecular BiologyNonsense-mediated Mrna DecayTranscriptional RegulationCell Regulation +21

The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Stefan Reber, Daniel Jutzi, Helen Lindsay, +9

Nucleic Acids Research

Llps FusMolecular BiologyCytoskeletonProtein Phase SeparationLiquid-liquid Phase Separation +15

Minor intron splicing is regulated by <scp>FUS</scp> and affected by <scp>ALS</scp> ‐associated <scp>FUS</scp> mutants

Stefan Reber, Jolanda Stettler, Giuseppe Filosa, +9

The EMBO Journal

Transcriptional RegulationNatural SciencesGeneticsRna SplicingMolecular Biology +6

FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention

Jack Humphrey, Nicol Birsa, Carmelo Milioto, +21

Nucleic Acids Research

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS

Marc Suárez‐Calvet, Manuela Neumann, Thomas Arzberger, +16

Acta Neuropathologica

Distinguish Ftld-fusChemical BiologyUnmethylated Fus ExhibitBiophysicsBiomolecular Engineering

Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation

Kathrin Meyer, Julien Marquis, Judith Trüb, +7

Human Molecular Genetics

Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy

Christian M. Schürch, Matthias A. Roelli, Stefan Förster, +11

Thyroid

ImmunologyImmune RegulationPathologyImmunoeditingImmunotherapeutics +18